Glycine to aspartic acid mutations at codon 13 of the c-Ki-ras gene in human gastrointestinal cancers.

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Article

Glycine to aspartic acid mutations at codon 13 of the c-Ki-ras gene in human gastrointestinal cancers.

Cancer research - 1 Feb 1990

Nagata Y, Abe M, Kobayashi K, Yoshida K, Ishibashi T, Naoe T, Nakayama E, Shiku H

Abstract excerpt

Point mutations of c-ras genes were analyzed in human gastrointestinal cancers. DNA obtained from the tissues was amplified by polymerase chain reaction and then analyzed by dot blot hybridization assay with oligonucleotide probes to detect mutations at codons 12, 13, and 61 of c-Ki-ras, c-Ha-ras...

Topics

Aspartic Acid
Base Sequence
DNA, Neoplasm
Gastrointestinal Neoplasms
Genes, ras
Glycine
Humans
Molecular Sequence Data
Mutation
Oligonucleotide Probes
Polymerase Chain Reaction
Proto-Oncogene Proteins
Proto-Oncogene Proteins p21(ras)

Source

Open in PubMed

Identifiers

PMID: 2404571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2404571-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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