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Article

Infrequent ras oncogene point mutations in renal cell carcinoma.

The Journal of urology - 1 Jan 1990

Nanus D M, Mentle I R, Motzer R J, Bander N H, Albino A P

Abstract excerpt

The role of ras oncogenes in the pathogenesis of renal cell carcinoma is unclear. We have previously shown that insertion of a mutated ras oncogene into cultured human proximal tubular cells, the normal counterpart of renal cell carcinomas, initiates a series of transformation events which result...

Topics

Adenoma
Carcinoma, Renal Cell
Cell Line
DNA, Neoplasm
Female
Genes, ras
Humans
Kidney Neoplasms
Male
Middle Aged
Mutation
Nucleic Acid Hybridization
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2403598
DOI: 10.1016/s0022-5347(17)39905-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2403598-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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