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Article

Infrequent ras oncogene point mutations in renal cell carcinoma.

The Journal of urology - 1 Jan 1990

Nanus D M, Mentle I R, Motzer R J, Bander N H, Albino A P

Abstract excerpt

The role of ras oncogenes in the pathogenesis of renal cell carcinoma is unclear. We have previously shown that insertion of a mutated ras oncogene into cultured human proximal tubular cells, the normal counterpart of renal cell carcinomas, initiates a series of transformation events which results in cells possessing a renal cancer phenotype. These data suggested a role for mutated ras genes in the initiation and...

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Identifiers

PMID: 2403598
DOI: 10.1016/s0022-5347(17)39905-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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