K-ras oncogene mutations in neoplasias of kidney transplanted patients: preliminary results with a new technique.

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Article

K-ras oncogene mutations in neoplasias of kidney transplanted patients: preliminary results with a new technique.

Anticancer research - 1 Jan 2000

Skalkeas G D, Spandidos D A, Kostakis A, Balafouta-Tseleni S, Choremi E, Iliopoulos D, Haliassos A

Abstract excerpt

K-ras oncogene activations by point mutations are frequent in many forms of human cancers but there is a special category of cancers occurring in immunosuppressed patients after kidney transplantation in which the frequency of K-ras oncogene activation has not been fully studied. We used a new sensitive and easy method for the detection of this mutation, and in 8 DNA samples studied from various neoplasias of 8...

Topics

Adult
Amino Acid Sequence
Codon
Female
Gene Amplification
Genes, ras
Humans
Immune Tolerance
Kidney Transplantation
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Neoplasms

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Sensitivity and Specificity

Source

Open in PubMed

Identifiers

PMID: 1685646

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1685646-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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