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Article

Replication of GWAS associations for GAK and MAPT in Parkinson's disease.

Annals of human genetics - 1 Mar 2011

Rhodes Shannon L, Sinsheimer Janet S, Bordelon Yvette, Bronstein Jeff M, Ritz Beate

Abstract excerpt

In the investigation of disease aetiology, the genome-wide association study (GWAS) provides a hypothesis-free investigation of the broader human genome and, as with all scientific investigations, replication is essential to validate any findings. To date, six GWAS have been performed to investigate the influence of common genetic variation in Parkinson's disease (PD) and only two associations have been...

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Source

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Identifiers

PMID: 21058943
DOI: 10.1111/j.1469-1809.2010.00616.x
PMCID: PMC3074465

Genes

MAPT
GAK
SNCA
MMRN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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Replication of GWAS associations for GAK and MAPT in Parkinson's disease.PMID 21058943Read ↗

Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.Semantic proximity Read ↗

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Genome-wide association study reveals genetic risk underlying Parkinson's disease.Semantic proximity Read ↗

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Meta-analysis of the association between variants in MAPT and neurodegenerative diseases.Semantic proximity Read ↗

Genomewide association study for susceptibility genes contributing to familial Parkinson disease.Semantic proximity Read ↗

Genome-wide association study stratified by<i>MAPT</i>haplotypes identifies potential novel loci in Parkinson’s diseaseSemantic proximity Read ↗

Microtubule-associated protein tau (MAPT) influences the risk of Parkinson's disease among Indians.Semantic proximity Read ↗

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