Article

Genome-wide association study stratified by<i>MAPT</i>haplotypes identifies potential novel loci in Parkinson’s disease

2023-04-15

Abstract excerpt

<h4>Objective</h4> To identify genetic factors that may modify the effects of the MAPT locus in Parkinson’s disease (PD). <h4>Methods</h4> We used data from the International Parkinson’s Disease Genomics Consortium (IPDGC) and the UK biobank (UKBB). We stratified the IPDGC cohort for carriers of the H1/H1 genotype (PD patients n=8,492 and controls n=6,765) and carriers of the H2 haplotype (with either H1/H2 or H2/...

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Literature Corpus work: f0404fcf-3ad0-527d-bd27-b2e47a5fc0d4
DOI: 10.1101/2023.04.14.23288478

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