Article
Genomewide association study for susceptibility genes contributing to familial Parkinson disease.
Human genetics - 1 Jan 2009
Pankratz Nathan, Wilk Jemma B, Latourelle Jeanne C, DeStefano Anita L, Halter Cheryl, Pugh Elizabeth W, Doheny Kimberly F, Gusella James F, Nichols William C, Foroud Tatiana, Myers Richard H
Abstract excerpt
Five genes have been identified that contribute to Mendelian forms of Parkinson disease (PD); however, mutations have been found in fewer than 5% of patients, suggesting that additional genes contribute to disease risk. Unlike previous studies that focused primarily on sporadic PD, we have performed the first genomewide association study (GWAS) in familial PD. Genotyping was performed with the Illumina...
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