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Article

Variants of ADAMTS1 modify the effectiveness of statins in reducing the risk of myocardial infarction.

Pharmacogenetics and genomics - 1 Dec 2010

Peters Bas J M, Rodin Andrei S, Klungel Olaf H, Stricker Bruno H Ch, de Boer Anthonius, Maitland-van der Zee Anke-Hilse

Abstract excerpt

OBJECTIVE: To investigate the influence of tagging single-nucleotide polymorphisms (SNPs) within candidate genes involved in the putative anti-inflammatory effects of statins on the effectiveness of statins in reducing the risk of myocardial infarction (MI). METHODS: We conducted a case-control study in a population-based registry of pharmacy records linked to hospital discharge records (PHARMO). Cases and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21037509
DOI: 10.1097/FPC.0b013e328340aded

Genes

ADAMTS1
ITGB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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