Article
Gene Polymorphisms Affect the Effectiveness of Atorvastatin in Treating Ischemic Stroke Patients.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2016
Yue Yun-Hua, Bai Xu-Dong, Zhang Hui-Jun, Li You-Mei, Hu Liang, Liu Ling-Yun, Mao Jie-Ping, Yang Xiao-Ying, Dila Na-Mu
Abstract excerpt
BACKGROUND/AIMS: The aim of the present study is to investigate whether the single nucleotide polymorphism (SNP) in lipid metabolism related genes would affect the effectiveness of atorvastatin in both Han and Uighur populations. METHODS: 200 ischemic stroke patients were treated with atorvastatin. The differences of blood lipid level and their ratios were measured. Six lipid related genes, HMGCR, APOA5, LPL,...
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