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Article

The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13 ) on the effectiveness of statins: the GenHAT study.

Pharmacogenetics and genomics - 1 May 2009

Maitland-van der Zee Anke-Hilse, Peters Bas J M, Lynch Amy I, Boerwinkle Eric, Arnett Donna K, Cheng Suzanne, Davis Barry R, Leiendecker-Foster Catherine, Ford Charles E, Eckfeldt John H

Abstract excerpt

BACKGROUND: Pharmacogenetic research has shown that genetic variation may influence statin responsiveness. Statins exert a variety of beneficial effects beyond lipid lowering, including antithrombotic effects, which contribute to the risk reduction of cardiovascular disease. Statins have been shown to influence the expression of coagulation factors II, V, VII, XII and XIII. AIM: Data from a large randomized...

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Identifiers

PMID: 19415820
DOI: 10.1097/fpc.0b013e32832933b7
PMCID: PMC2701506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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