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Article

Genetic variation in the renin--angiotensin system, use of renin--angiotensin system inhibitors and the risk of myocardial infarction.

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Sept 2011

Maitland-van der Zee Anke-Hilse, van Wieren-de Wijer Diane Bma, de Boer Anthonius, Kroon Abraham A, de Leeuw Peter W, Schiffers Paul, Janssen Rob Gjh, Psaty Bruce M, van Duijn Cornelia M, Stricker Bruno Hch, Klungel Olaf H

Abstract excerpt

INTRODUCTION: This study investigated whether variation in the genes encoding for ACE, AGT and AGTR1 modifies the risk of myocardial infarction (MI) related to ACE inhibitors and AT II antagonists. METHODS: A nested case-control study among users of antihypertensive drugs, in whom the polymorphisms ACE-G4656C, ACE-T3892C, AGT-C235T and AGTR1-A1166C were genotyped. RESULTS: Among 613 cases and 3630 controls, the...

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Share to Angiotensin-Converting Enzyme Inhibitors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21163865
DOI: 10.1177/1470320310391834

Genes

ACE
AGTR1
AGT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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