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Article

Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction.

Pharmacogenomics - 1 Aug 2010

Peters Bas J M, Rodin Andrei S, Klungel Olaf H, van Duijn Cornelia M, Stricker Bruno H Ch, van't Slot Ruben, de Boer Anthonius, Maitland-van der Zee Anke-Hilse

Abstract excerpt

AIMS: Genetic variability within the SLCO1B1 and ABCB1 transporter genes has been associated with modification of statin effectiveness in cholesterol management. MATERIALS & METHODS: We conducted a case-control study using a population-based registry of pharmacy records linked to the hospital discharge records. Within a hypercholesterolemic cohort, we included 668 myocardial infarction cases and 1217 controls....

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Source

Identifiers

PMID: 20712525
DOI: 10.2217/pgs.10.81

Genes

ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction.PMID 20712525Read ↗

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