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Article

Polymorphisms in CYP450 Genes and the Therapeutic Effect of Atorvastatin on Ischemic Stroke: A Retrospective Cohort Study in Chinese Population.

Clinical therapeutics - 1 Mar 2018

Peng Chen, Ding Ying, Yi Xin, Shen Yupei, Dong Zhiqiang, Cao Limei, Li Qiang, Ren Haiyan, He Lin, Zhou Daizhan, Chen Xu

Abstract excerpt

PURPOSE: Ischemic stroke (IS) is one of the most common neurologic diseases and is the main cause of death and disability in the Chinese population. This retrospective cohort study was performed to elucidate the relationship between single nucleotide polymorphisms (SNPs) in cytochrome P450 genes and the therapeutic effect of atorvastatin. METHODS: A total of 192 cases of IS were enrolled in the study. All...

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PMID: 29500141
DOI: 10.1016/j.clinthera.2018.02.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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