Article
Effects of ABCG2 and SLCO1B1 gene variants on inflammation markers in patients with hypercholesterolemia and diabetes mellitus treated with rosuvastatin.
European journal of clinical pharmacology - 1 Jul 2020
Zhang Dan, Ding Yangming, Wang Xiaoxue, Xin Wenyu, Du Wenwen, Chen Wenqian, Zhang Xianglin, Li Pengmei
Abstract excerpt
PURPOSE: Dysregulation of angiogenesis and inflammation play important roles in the development of atherosclerosis. Rosuvastatin (RST) was widely used in atherosclerosis therapy. Genetic variations of transporters may affect the rosuvastatin concentration in plasma and reflect different clinical treatment. The aim of this study was to explore the drug transport related single-nucleotide polymorphisms (SNPs) on...
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