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Article

Association of serotonin transporter gene variation with smoking, chronic obstructive pulmonary disease, and its depressive symptoms.

Journal of human genetics - 1 Jan 2011

Ishii Takeo, Wakabayashi Ritsuko, Kurosaki Hiroko, Gemma Akihiko, Kida Kozui

Abstract excerpt

A serotonin transporter gene, SLC6A4, is thought to be related to nicotine dependence and depression, one of the comorbidities of chronic obstructive pulmonary disease (COPD). To investigate the association between SLC6A4 variation and tobacco consumption, susceptibility to COPD, and depression status. In all, 247 patients with COPD and 119 control subjects were genotyped for 5 tag single-nucleotide polymorphisms...

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Identifiers

PMID: 20981038
DOI: 10.1038/jhg.2010.133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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