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Article

Association of 5-hydroxytryptamine (serotonin) receptor 4 (5-HTR4) gene polymorphisms with asthma.

Respirology (Carlton, Vic.) - 1 May 2011

Kim Tae-Hoon, An Sung-Hye, Cha Ji-Yeon, Shin Eun-Kyong, Lee Ji-Yeon, Yoon Sang-Hyuk, Lee Young-Mok, Uh Soo-Taek, Park Sung-Woo, Park Jong-Sook, Kim Young-Hoon, Choi Jae-Sung, Lee Soo-Ok, Park Byung-Lae, Shin Hyung-Doo, Park Choon-Sik

Abstract excerpt

BACKGROUND AND OBJECTIVE: The neurotransmitter, 5-hydroxytryptamine, acts as an immunomodulator by stimulating the release of inflammatory cytokines and regulating the function of dendritic cells and monocytes. The 5-hydroxytryptamine receptor 4 (HTR4) gene is located in a region previously linked to an increased risk of asthma and atopy. The aim of this study was to investigate the association between HTR4 and...

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Source

Identifiers

PMID: 21382128
DOI: 10.1111/j.1440-1843.2011.01963.x

Genes

HTR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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