Article
[Association of 5-hydroxytryptamine transporter gene polymorphism with asthma and comorbid depression].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2009
Wang Lan, Mo Zu-cong, Wang Yan, Ji Yu-lin
Abstract excerpt
OBJECTIVE: To explore the molecular genetic mechanism of complicating depression in asthma by detecting two gene polymorphisms of 5-hydroxytryptamine transporter (5-HTTLPR/Stin2) gene. METHODS: One hundred fifty-six adults with asthma were collected, and divided into group of asthma with depression (HAMD score > or = 8) and group of asthma without depression or single asthma (HAMD score <8) according to the score...
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