Article
Sequence variants and haplotype analysis of serotonin transporter gene and association with bipolar affective disorder in Taiwan.
Pharmacogenetics - 1 Mar 2004
Sun H Sunny, Wang Hui-Chung, Lai Te-Jen, Wang Tso-Jen, Li Chih-Ming
Abstract excerpt
OBJECTIVES: Serotonin transporter (SLC6A4) is responsible for serotonin re-uptake into presynaptic terminals, thus fine-tuning brain serotonergic neurotransmission. Current studies have found associations of SLC6A4 polymorphisms with several psychiatric traits including bipolar affective disorder (BPD) in various populations; however, studies with contradictory results were also reported. This study examined the...
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