Article
Association study of serotonin transporter gene polymorphisms with obstructive sleep apnea syndrome in Chinese Han population.
Sleep - 1 Nov 2008
Yue Weihua, Liu Huiguo, Zhang Jishui, Zhang Xianghui, Wang Xiaoping, Liu Tieqiao, Liu Pozi, Hao Wei
Abstract excerpt
BACKGROUND: Since the serotonin (5-HT) is associated with circadian rhythm and breathing regulation, the serotonin transporter (5-HTT), which plays an important role in serotoninergic transmission, might be a strong candidate gene in the pathogenesis of obstructive sleep apnea syndrome (OSAS). OBJECTIVE: To investigate the association of 5-HTT gene polymorphisms with OSAS and clinical characteristics. METHODS: We...
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