Article
Serotonin transporter gene, depressive symptoms, and interleukin-6.
Circulation. Cardiovascular genetics - 1 Dec 2009
Su Shaoyong, Zhao Jinying, Bremner J Douglas, Miller Andrew H, Tang Weining, Bouzyk Mark, Snieder Harold, Novik Olga, Afzal Nadeem, Goldberg Jack, Vaccarino Viola
Abstract excerpt
BACKGROUND: We explored the relationship of genetic variants of the serotonin transporter gene SLC6A4, a key regulator of the serotonergic neurotransmission, with both depressive symptoms and plasma interleukin-6 (IL-6) levels. METHODS AND RESULTS: We genotyped 20 polymorphisms in 360 male twins (mean age, 54 years) from the Vietnam Era Twin Registry. Current depressive symptoms were measured with the Beck...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.