Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism of the serotonin transporter gene and pulmonary hypertension in chronic obstructive pulmonary disease.

Circulation - 14 Oct 2003

Eddahibi Saadia, Chaouat Ari, Morrell Nicholas, Fadel Elie, Fuhrman Claire, Bugnet Anne-Sophie, Dartevelle Philippe, Housset Bruno, Hamon Michel, Weitzenblum E, Adnot Serge

Abstract excerpt

BACKGROUND: The serotonin transporter (5-HTT) is involved in the pulmonary artery smooth muscle hyperplasia that leads to pulmonary hypertension (PH). Because hypoxia and 5-HTT gene polymorphism control 5-HTT expression, we examined 5-HTT gene polymorphism and PH in hypoxemic patients with advanc...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hyperplasia
Share to Hypertension, Pulmonary
Share to Hypoxia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Glycoproteins

Share to Membrane Transport Proteins

Share to Pulmonary Disease, Chronic Obstructive

Share to Serotonin Plasma Membrane Transport Proteins

Share to Tunica Media

Source

Identifiers

PMID: 14530202
DOI: 10.1161/01.CIR.0000091409.53101.E8

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14530202-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism of the serotonin transporter gene and pulmonary hypertension in chronic obstructive pulmonary disease.PMID 14530202Read ↗

Repeat length polymorphism of the serotonin transporter gene influences pulmonary artery pressure in heart failure.Semantic proximity Read ↗

Associations between endothelial nitric oxide synthase A/B, angiotensin converting enzyme I/D and serotonin transporter L/S gene polymorphisms with pulmonary hypertension in COPD patients.Semantic proximity Read ↗

Serotonin-induced smooth muscle hyperplasia in various forms of human pulmonary hypertension.Semantic proximity Read ↗

Serotonin transporter polymorphisms in familial and idiopathic pulmonary arterial hypertension.Semantic proximity Read ↗

Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension.Semantic proximity Read ↗

Association of serotonin transporter gene variation with smoking, chronic obstructive pulmonary disease, and its depressive symptoms.Semantic proximity Read ↗

Hyperplasia of pulmonary artery smooth muscle cells is causally related to overexpression of the serotonin transporter in primary pulmonary hypertension.Semantic proximity Read ↗

Polymorphisms in the serotonin transporter protein (SERT) gene in patients with pulmonary arterial hypertension.Semantic proximity Read ↗

Association between serotonin transporter (SERT) gene polymorphism and idiopathic pulmonary arterial hypertension: a meta-analysis and review of the literature.Semantic proximity Read ↗

Pathobiology of pulmonary arterial hypertension.Semantic proximity Read ↗

5-HTT, BMPR2, EDN1, ENG, KCNA5 gene polymorphisms and susceptibility to pulmonary arterial hypertension: A meta-analysis.Semantic proximity Read ↗

Association of serotonin transporter gene polymorphism with obstructive sleep apnea syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.