Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fate or coincidence: do COPD and major depression share genetic risk factors?

Human molecular genetics - 12 May 2021

Martucci Victoria L, Richmond Bradley, Davis Lea K, Blackwell Timothy S, Cox Nancy J, Samuels David, Velez Edwards Digna, Aldrich Melinda C

Abstract excerpt

Major depressive disorder (MDD) is a common comorbidity in chronic obstructive pulmonary disease (COPD), affecting up to 57% of patients with COPD. Although the comorbidity of COPD and MDD is well established, the causal relationship between these two diseases is unclear. A large-scale electronic health record clinical biobank and genome-wide association study summary statistics for MDD and lung function traits...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Tennessee
Share to Comorbidity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Depressive Disorder, Major

Share to Genome-Wide Association Study

Share to Linkage Disequilibrium

Share to Multifactorial Inheritance

Share to Pulmonary Disease, Chronic Obstructive

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 33704461
DOI: 10.1093/hmg/ddab068
PMCID: PMC8120137

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fate or coincidence: do COPD and major depression share genetic risk factors?PMID 33704461Read ↗

<i>De novo</i> discovery of traits co-occurring with chronic obstructive pulmonary diseaseSemantic proximity Read ↗

De novo discovery of traits co-occurring with chronic obstructive pulmonary disease.Semantic proximity Read ↗

Assessing the comorbidity between asthma and depression through polygenic risk scoring and time-to-event models.Semantic proximity Read ↗

GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort.Semantic proximity Read ↗

Assessing causality between chronic obstructive pulmonary disease with depression: A bidirectional Mendelian randomization studySemantic proximity Read ↗

Genetic Architecture of Comorbidity Between Chronic Obstructive Pulmonary Disease and Cardiovascular Diseases: Exploring Shared Mechanisms and Potential Therapeutic Targets.Semantic proximity Read ↗

COPD and Depression—The Vicious Mental CycleSemantic proximity Read ↗

Association between depression and COPD: results from the NHANES 2013–2018 and a bidirectional Mendelian randomization analysisSemantic proximity Read ↗

Shared Genetic Liability Between Major Depressive Disorder and Atopic Diseases.Semantic proximity Read ↗

Identifying COPD subtypes using multi-trait geneticsSemantic proximity Read ↗

A twin study of depression and nicotine dependence: shared liability or causal relationship?Semantic proximity Read ↗

Genetic correlation and causal associations between psychiatric disorders and lung cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.