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Article

Hippocampal atrophy rates and CSF biomarkers in elderly APOE2 normal subjects.

Neurology - 30 Nov 2010

Chiang G C, Insel P S, Tosun D, Schuff N, Truran-Sacrey D, Raptentsetsang S T, Jack C R, Aisen P S, Petersen R C, Weiner M W

Abstract excerpt

OBJECTIVE: To determine whether elderly normal APOE E2 (APOE2) carriers exhibit slower rates of hippocampal atrophy and memory decline compared to APOE3/3 carriers. We also determined whether APOE2 carriers have less Alzheimer pathology as reflected by CSF biomarkers. METHODS: We included longitu...

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Source

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Identifiers

PMID: 20980669
DOI: 10.1212/WNL.0b013e3181ffe4d1
PMCID: PMC3014234

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20980669-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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