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Article

Manipulating the permeation of charged compounds through the MscL nanovalve.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jan 2011

Yang Li-Min, Blount Paul

Abstract excerpt

MscL is a bacterial mechanosensor that serves as a biological emergency release valve, releasing cytoplasmic solutes to the environment on osmotic downshock. Previous studies have recognized that this channel has properties that make it ideal for use as a triggered nanovalve for vesicular-based targeted drug-release devices. One can even change the modality of the sensor. Briefly, the introduction of charges into...

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Identifiers

PMID: 20930114
DOI: 10.1096/fj.10-170076
PMCID: PMC3005423

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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