Article
Engineered three-dimensional liver mimics recapitulate critical rat-specific bile acid pathways.
Tissue engineering. Part A - 1 Mar 2011
Detzel Christopher J, Kim Yeonhee, Rajagopalan Padmavathy
Abstract excerpt
A critical hepatic function is the maintenance of optimal bile acid (BA) compositions to achieve cholesterol homeostasis. BAs are rarely quantified to assess hepatic phenotype in vitro since existing analytical techniques have inadequate resolution. We report a detailed investigation into the bio...
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