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3D culture models to study pathophysiology of steatotic liver disease.

Atherosclerosis - 1 Jun 2024

Caddeo Andrea, Maurotti Samantha, Kovooru Lohitesh, Romeo Stefano

Abstract excerpt

Steatotic liver disease (SLD) refers to a spectrum of diseases caused by hepatic lipid accumulation. SLD has emerged as the leading cause of chronic liver disease worldwide. Despite this burden and many years, understanding the pathophysiology of this disease is challenging due to the inaccessibility to human liver specimens. Therefore, cell-based in vitro systems are widely used as models to investigate the...

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PMID: 38677899
DOI: 10.1016/j.atherosclerosis.2024.117544

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