Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Essential role of B7-H1 in double-stranded RNA-induced augmentation of an asthma phenotype in mice.

American journal of respiratory cell and molecular biology - 1 Jul 2011

Matsumoto Koichiro, Kan-O Keiko, Eguchi-Tsuda Miyuki, Fukuyama Satoru, Asai Yukari, Matsumoto Takafumi, Moriwaki Atsushi, Matsunaga Yuko, Tsutsui Hiroko, Kawai Taro, Takeuchi Osamu, Akira Shizuo, Yagita Hideo, Azuma Miyuki, Nakanishi Yoichi, Inoue Hiromasa

Abstract excerpt

Clinical and epidemiological studies have shown the contribution of viral infection to the development of allergic asthma. Many RNA viruses, pathogenic for the respiratory tract, generate double-stranded (ds)RNA during their replication. Typical innate immune responses triggered by dsRNA involve the endosomal and cytoplasmic pathways. The former is mediated by Toll/IL-1R domain-containing adaptor inducing IFN-β...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Vesicular Transport
Share to B7-1 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to B7-H1 Antigen

Share to CD8-Positive T-Lymphocytes

Share to Dendritic Cells

Share to Interleukin-13

Share to Ovalbumin

Share to RNA, Double-Stranded

Source

Identifiers

PMID: 20802088
DOI: 10.1165/rcmb.2009-0450OC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Essential role of B7-H1 in double-stranded RNA-induced augmentation of an asthma phenotype in mice.PMID 20802088Read ↗

A viral PAMP double‐stranded RNA induces allergen‐specific Th17 cell response in the airways which is dependent on VEGF and IL‐6Semantic proximity Read ↗

B7-H3 participates in the development of Asthma by augmentation of the inflammatory response independent of TLR2 pathwaySemantic proximity Read ↗

Phenotype and severity of asthma determines bronchial epithelial immune responses to a viral mimic.Semantic proximity Read ↗

Toll-Like Receptor–Mediated Airway IL-17C Enhances Epithelial Host Defense in an Autocrine/Paracrine MannerSemantic proximity Read ↗

A combination TLR7/8 and RIG-I agonist adjuvant reverts asthmatic allergic sensitization and prevents aggravated influenza infection in OVA-sensitized miceSemantic proximity Read ↗

The TLR4-TRIF pathway can protect against the development of experimental allergic asthma.Semantic proximity Read ↗

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways.Semantic proximity Read ↗

Amplification of poly(I:C)-induced interleukin-6 production in human bronchial epithelial cells by priming with interferon-γSemantic proximity Read ↗

Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons.Semantic proximity Read ↗

Double-stranded RNA evokes exacerbation in a mouse model of corticosteroid refractory asthma.Semantic proximity Read ↗

P2rx4 deficiency in mice alleviates allergen-induced airway inflammation.Semantic proximity Read ↗

Toll-like receptor 7 function is reduced in adolescents with asthmaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.