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Article

P2rx4 deficiency in mice alleviates allergen-induced airway inflammation.

Oncotarget - 6 Dec 2016

Zech Andreas, Wiesler Benjamin, Ayata Cemil Korcan, Schlaich Tilmann, Dürk Thorsten, Hoßfeld Madelon, Ehrat Nicolas, Cicko Sanja, Idzko Marco

Abstract excerpt

Compelling evidences point out a crucial role for extracellular nucleotides such as adenosine triphosphate (ATP) during inflammatory conditions. Once released into the extracellular space, ATP modulates migration, maturation and function of various inflammatory cells via activating of purinergic receptors of the P2Y- and P2X- family. P2RX4 is an ATP-guided ion channel expressed on structural cells such as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27863396
DOI: 10.18632/oncotarget.13375
PMCID: PMC5348320

Genes

NLRP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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