Article

A combination TLR7/8 and RIG-I agonist adjuvant reverts asthmatic allergic sensitization and prevents aggravated influenza infection in OVA-sensitized mice

2025-06-26

Abstract excerpt

<h4>ABSTRACT</h4> Allergen-specific immunotherapy (AIT) is the only disease-modifying treatment currently available to treat allergy. However, it has limitations, as most allergens are poorly immunogenic, resulting in an AIT process that can take years. Therefore, adjuvant selection becomes critical to achieve a more efficacious therapy. Our group has developed and tested an amphiphilic TLR7/8 agonist (IMDQ) and...

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Literature Corpus work: 841276f0-dd9c-5813-8980-40a563017bc6
DOI: 10.1101/2025.06.23.659362

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