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Article

Phenotype and severity of asthma determines bronchial epithelial immune responses to a viral mimic.

The European respiratory journal - 1 Jul 2022

Porsbjerg Celeste, Nieto-Fontarigo Juan Jose, Cerps Samuel, Ramu Sangheeta, Menzel Mandy, Hvidtfeldt Morten, Silberbrandt Alexander, Frøssing Laurits, Klein Ditte, Sverrild Asger, Uller Lena

Abstract excerpt

BACKGROUND: Asthma is characterised by an aggravated immune response to respiratory viral infections. This phenomenon is a clinically well-recognised driver of acute exacerbations, but how different phenotypes of asthma respond immunologically to viruses is unclear. OBJECTIVES: To describe the association between different phenotypes and severity of asthma and bronchial epithelial immune responses to viral...

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Identifiers

PMID: 34916261
DOI: 10.1183/13993003.02333-2021

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