Article

Amplification of poly(I:C)-induced interleukin-6 production in human bronchial epithelial cells by priming with interferon-γ

2023-09-11

Abstract excerpt

Proinflammatory cytokine interleukin (IL)-6 was associated with disease severity in patients with COVID-19. The mechanism underlying the excessive production of IL-6 by SARS-Cov-2 infection remains unclear. Respiratory viruses initially infect alveolar epithelial cells that produce various immunomodulatory inflammatory mediators. Here, we show that pretreatment of human bronchial epithelial cells (NCl-H292) with i...

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Literature Corpus work: e3b869b6-0413-51ea-bb6f-511bfdb949bd
DOI: 10.21203/rs.3.rs-3234363/v1

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