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Article

B7-H3 participates in the development of Asthma by augmentation of the inflammatory response independent of TLR2 pathway

17 Jan 2017

Abstract excerpt

B7-H3, a new member of the B7 superfamily, acts as both a T cell costimulator and coinhibitor. Recent studies identified B7-H3 plays a critical role in the development of asthma. But the definitive mechanism is not clear. In this study, we further report that B7-H3 participates in the development of OVA-induced asthma in a murine model. And study its mechanism through the vitro and vivo experiment. Exogenous...

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PMID: 28094276
DOI: 10.1038/srep40398

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