Article
Spontaneous and radiation-induced genetic instability of heteromyeloma hybridoma cells.
Molecular biology & medicine - 1 Dec 1990
Harris J F, Koropatnick J, Pearson J
Abstract excerpt
We have examined the genetic stability of heteromyeloma cells both spontaneously and following ionizing radiation. Clones of E10 cells (SHM-D33 heteromyeloma X human lymphoblastoid) were examined for the stability of human immunoglobulin (Ig) production (mu, lambda), relative human and mouse DNA,...
Topics
- Animals
- Antibodies, Monoclonal
- Clone Cells
- DNA
- DNA Probes
- Gene Expression
- Humans
- Hybridomas
- Immunohistochemistry
- Mice
- Mutation