Article
Analysis of mutations introduced into the chromosomal immunoglobulin mu gene.
Somatic cell and molecular genetics - 1 Jul 1993
Baker M D, Read L R
Abstract excerpt
We have introduced a pSV2neo-derived vector that contains a 2-base-pair (bp) deletion in its immunoglobulin mu gene constant region into hybridoma cells bearing a single copy of the wild-type chromosomal immunoglobulin mu gene. Homologous recombination between the transferred mutant C mu region and the wild-type chromosomal C mu region is expected to introduce the 2-bp deletion into the chromosomal mu gene,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.