Analysis of mutations introduced into the chromosomal immunoglobulin mu gene.

doi:10.1007/BF01232743

Back to search

Article

Analysis of mutations introduced into the chromosomal immunoglobulin mu gene.

Somatic cell and molecular genetics - 1 Jul 1993

Baker M D, Read L R

Abstract excerpt

We have introduced a pSV2neo-derived vector that contains a 2-base-pair (bp) deletion in its immunoglobulin mu gene constant region into hybridoma cells bearing a single copy of the wild-type chromosomal immunoglobulin mu gene. Homologous recombination between the transferred mutant C mu region a...

Topics

Animals
Base Sequence
DNA
Gene Deletion
Hybridomas
Immunoglobulin Constant Regions
Immunoglobulin M
Immunoglobulin mu-Chains
Mice
Mutation
Picrates
Precipitin Tests
Recombination, Genetic
Restriction Mapping
Transformation, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.