Article
Intrachromosomal recombination between well-separated, homologous sequences in mammalian cells.
Genetics - 1 Jun 1999
Baker M D, Read L R, Ng P, Beatty B G
Abstract excerpt
In the present study, we investigated intrachromosomal homologous recombination in a murine hybridoma in which the recipient for recombination, the haploid, endogenous chromosomal immunoglobulin mu-gene bearing a mutation in the constant (Cmu) region, was separated from the integrated single copy wild-type donor Cmu region by approximately 1 Mb along the hybridoma chromosome. Homologous recombination between the...
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