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Article

HLA gene and phenotype data of 60 insulin-dependent diabetic patients from north-eastern Italy. A negative association with DR5 rather than DR2?

Acta diabetologica latina - 1 Jan 2000

Maffeis C, Ciaffoni S, Gonfiatini E, Roata C, Pinelli L

Abstract excerpt

The purpose of our study was to evaluate what kind of relationships exist between HLA antigens and insulin-dependent diabetes mellitus (IDDM), in 20 families and in 40 single patients coming from and living in North Eastern Italy. The subjects studied show a strong association with HLA-DR3 and/or -DR4; at least one of these antigens is present in 88% of the diabetic subjects; this confirms that these antigens...

Topics

Alleles
Diabetes Mellitus, Type 1
Family
HLA Antigens
HLA-DR2 Antigen
HLA-DR5 Antigen
Haplotypes
Humans
Italy
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2075785
DOI: 10.1007/BF02581334

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2075785-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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