A new HLA-DR2 extended haplotype is involved in insulin-dependent diabetes mellitus susceptibility.

doi:10.1016/0198-8859(91)90021-z

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Article

A new HLA-DR2 extended haplotype is involved in insulin-dependent diabetes mellitus susceptibility.

Human immunology - 1 Jul 1991

Carcassi C, Trucco G, Trucco M, Contu L

Abstract excerpt

To ascertain why HLA-DR2 seems to confer only a moderate resistance to insulin-dependent diabetes mellitus (IDDM) in the high-incidence population of Sardinia, Italy, 32 families having one individual affected with IDDM (the proband) and 31 families without IDDM history were randomly selected fro...

Topics

Autoimmune Diseases
Base Sequence
Diabetes Mellitus, Type 1
Disease Susceptibility
Ethnicity
Gene Frequency
Genetic Predisposition to Disease
HLA-DQ Antigens
HLA-DR2 Antigen
Haplotypes
Humans
Immunity, Innate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Incidence

Italy

Molecular Sequence Data

Oligonucleotide Probes

Polymerase Chain Reaction

White People

Source

Open in PubMed

Identifiers

PMID: 1890017
DOI: 10.1016/0198-8859(91)90021-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1890017-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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