Article
Genetic predisposition and IDDM in Greece.
Genetic counseling (Geneva, Switzerland) - 1 Jan 1993
Karayanni C, Anastasiadou V, Spyropoulou M, Delis D, Khalil I, Lepage V, Papanicolaoy M, Varla M, Stavropoulou A, Bartsocas C S
Abstract excerpt
Serological typing of HLA-DR antigens was performed on 116 patients with IDDM and 380 healthy controls. As expected a high incidence of HLA-DR3 and DR4 antigens was observed in patients with IDDM. However, the HLA-DR2 antigen, which rarely occurs in IDDM and is considered to confer protection against IDDM, was found in equal distribution (35%) in both patients and controls. HLA-DQ genotype analysis in 10 children...
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