Excess of maternal HLA-DR3 antigens in HLA DR3,4 positive type 1 (insulin-dependent) diabetic patients.

doi:10.1007/BF00404094

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Article

Excess of maternal HLA-DR3 antigens in HLA DR3,4 positive type 1 (insulin-dependent) diabetic patients.

Diabetologia - 1 Jul 1990

Deschamps I, Hors J, Clerget-Darpoux F, Gardais E, Robert J J, Marcelli-Berge A, Lestradet H, Dausset J

Abstract excerpt

The susceptibility determinants of Type 1 (insulin-dependent) diabetes mellitus are known to be associated with both HLA-DR3 and DR4. In our study we wished to determine if the parental origin of these antigens could influence susceptibility to the disease. We analysed the inheritance of DR3 and...

Topics

Adult
Child
Diabetes Mellitus, Type 1
Family
Female
Genetic Carrier Screening
Genotype
HLA-DR3 Antigen
HLA-DR4 Antigen
Histocompatibility Testing
Humans
Male
Mothers
Phenotype
Risk Factors

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