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Article

Multi-locus analysis of HLA class II genes in DR2-positive IDDM haplotypes in Finland. The "Childhood Diabetes in Finland" (DiMe) Study Group.

Tissue antigens - 1 Jan 1994

Reijonen H, Ilonen J, Akerblom H K, Knip M, Dosch H M

Abstract excerpt

In this study we characterized the haplotypes found in IDDM patients that normally confer resistance to the disease in order to localize the polymorphisms relevant for the protection. We studied 15 DR2-positive subjects with IDDM for their DRB1, DRB5 and DQB1 genes using RFLP, polymerase chain re...

Topics

Alleles
Base Sequence
Chromosome Mapping
DNA
Diabetes Mellitus, Type 1
Finland
Gene Frequency
HLA-DR2 Antigen
Haplotypes
Histocompatibility Antigens Class II
Humans
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 7912856
DOI: 10.1111/j.1399-0039.1994.tb02289.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7912856-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Multi-locus analysis of HLA class II genes in DR2-positive IDDM haplotypes in Finland. The "Childhood Diabetes in Finland" (DiMe) Study Group.PMID 7912856Read ↗

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