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Article

5' insulin gene polymorphism confers risk to IDDM independently of HLA class II susceptibility.

Diabetes - 1 Jun 1993

van der Auwera B J, Heimberg H, Schrevens A F, van Waeyenberge C, Flament J, Schuit F C

Abstract excerpt

The polymorphic variable number of tandem repeats in the 5' upstream region of the human insulin gene is a well-known non-human leukocyte antigen locus contributing to genetic susceptibility to IDDM. Controversy exists about the question as to whether INS susceptibility haplotypes are or are not preferentially inherited together with HLA-DR4 haplotypes. We investigated whether genetic interaction between INS and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8495808
DOI: 10.2337/diab.42.6.851

Genes

INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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5' insulin gene polymorphism confers risk to IDDM independently of HLA class II susceptibility.PMID 8495808Read ↗

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