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Lgl, the SWH pathway and tumorigenesis: It's a matter of context & competition!

Cell cycle (Georgetown, Tex.) - 15 Aug 2010

Grzeschik Nicola A, Parsons Linda M, Richardson Helena E

Abstract excerpt

Loss of function of the neoplastic tumors suppressors, lgl, scrib and dlg or overexpression of the apical polarity components, Crumbs and atypical protein kinase C (aPKC), are associated with polarity loss and tissue overgrowth, however, the mechanism behind these effects is poorly understood. In...

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Identifiers

PMID: 20724829
DOI: 10.4161/cc.9.16.12633

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20724829-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Lgl, the SWH pathway and tumorigenesis: It's a matter of context & competition!PMID 20724829Read ↗

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