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Article

ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels.

Clinical genetics - 1 Feb 2002

Zwarts K Y, Clee S M, Zwinderman A H, Engert J C, Singaraja R, Loubser O, James E, Roomp K, Hudson T J, Jukema J W, Kastelein J J P, Hayden M R

Abstract excerpt

The authors have previously shown that individuals heterozygous for ABCA1 mutations have decreased high density lipoprotein cholesterol, increased triglycerides and an increased frequency of coronary artery disease (CAD), and that single nucleotide polymorphisms (SNPs) in the coding region of the ABCA1 gene significantly impact plasma lipid levels and the severity of CAD in the general population. They have now...

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Source

Identifiers

PMID: 11940086
DOI: 10.1034/j.1399-0004.2002.610206.x

Genes

ABCA1
CAD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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