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Article

The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy.

The pharmacogenomics journal - 1 Feb 2010

Romaine S P R, Bailey K M, Hall A S, Balmforth A J

Abstract excerpt

Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are well established in the treatment of hypercholesterolaemia and the prevention of coronary artery disease. Despite this, there is wide inter-individual variability in response to statin therapy, in terms of both lipid-lowering and adverse drug reactions. The major site of statin action is within hepatocytes and recent interest has focussed on...

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PMID: 19884908
DOI: 10.1038/tpj.2009.54

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy.PMID 19884908Read ↗

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