Possible gene-gender interaction between the SLCO1B1 polymorphism and statin treatment efficacy.

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Article

Possible gene-gender interaction between the SLCO1B1 polymorphism and statin treatment efficacy.

Neuro endocrinology letters - 1 Jan 2012

Hubacek Jaroslav A, Dlouha Dana, Adámkova Vera, Lanska Vera, Ceska Richard, Vrablik Michal

Abstract excerpt

OBJECTIVES: A significant inter-individual variability in statin treatment efficacy is likely to have a strong genetic background. A candidate gene with the potential to influence statin treatment efficacy is SLCO1B1. This gene codes for the solute carrier organic anion transporter, which has been shown to regulate the hepatic uptake of statins and some other drugs. MATERIALS AND METHODS: The SLCO1B1 rs4149056...

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PMID: 23183505

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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