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Article

Genetic variation in ABCA1 predicts ischemic heart disease in the general population.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2008

Frikke-Schmidt Ruth, Nordestgaard Børge G, Jensen Gorm B, Steffensen Rolf, Tybjaerg-Hansen Anne

Abstract excerpt

OBJECTIVE: We tested the hypothesis that 6 nonsynonymous single nucleotide polymorphisms (SNPs) in ATP-Binding-Cassette transporter A1 (ABCA1) affect risk of ischemic heart disease (IHD) in the general population. METHODS AND RESULTS: We genotyped 9259 individuals from the Danish general population followed for 25 years. Two SNPs (V771M and V825I) were previously associated with increases in HDL-C, 1 (R1587K)...

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Source

Identifiers

PMID: 17951323
DOI: 10.1161/ATVBAHA.107.153858

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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