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Article

Associations between four polymorphisms of the SLCO1B1 and effectiveness of the statins: a meta-analysis.

Pharmacogenetics and genomics - 1 Jun 2023

Nguyen Hong Ha, Nguyen Cuc Thi Thu, Mai Tran Ngoc Phuong, Huong Phung Thanh

Abstract excerpt

OBJECTIVE: Statins are the first-choice therapy for dyslipidemia, but their effectiveness can be influenced by genetic polymorphisms. This study was conducted to assess the association of variants of the solute carrier anion transporter family 1B1 (SLCO1B1) gene, which encodes a transporter involving the hepatic clearance of the statins and their therapeutic efficacy. METHOD: A systematic review was performed on...

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Share to Cholesterol, LDL
Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Liver-Specific Organic Anion Transporter 1

Share to Organic Anion Transporters

Share to Polymorphism, Single Nucleotide

Share to Simvastatin

Source

Identifiers

PMID: 37098851
DOI: 10.1097/FPC.0000000000000490

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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