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Article

Tyrosine phosphorylation of vinculin at position 1065 modifies focal adhesion dynamics and cell tractions.

Biochemical and biophysical research communications - 3 Sept 2010

Küpper Kevin, Lang Nadine, Möhl Christoph, Kirchgessner Norbert, Born Simone, Goldmann Wolfgang H, Merkel Rudolf, Hoffmann Bernd

Abstract excerpt

Focal adhesions (FAs) connect the cellular actin cytoskeleton via integrin with the extracellular matrix. They comprise of many structural and signaling proteins which are highly dynamic, well regulated, and responsible for the sensing of physical properties from the environment. Vinculin is a protein that incorporates all these functions. Here, we investigated the phosphorylation of Y1065 in the...

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Identifiers

PMID: 20678470
DOI: 10.1016/j.bbrc.2010.07.110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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