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Article

Role of vinculin in regulating focal adhesion turnover.

European journal of cell biology - 1 Jun 2006

Saunders Ruth M, Holt Mark R, Jennings Lisa, Sutton Deborah H, Barsukov Igor L, Bobkov Andrey, Liddington Robert C, Adamson Eileen A, Dunn Graham A, Critchley David R

Abstract excerpt

Although vinculin (-/-) mouse embryo fibroblasts assemble focal adhesions (FAs), they spread more slowly, less extensively, and close a wound more rapidly than vinculin (+/+) cells. To investigate the structure and dynamics of FAs in these cells, we used real-time interference reflection microscopy (IRM) thus avoiding the need to express exogenous GFP-tagged FA proteins which may be misregulated. This showed that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16584805
DOI: 10.1016/j.ejcb.2006.01.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of vinculin in regulating focal adhesion turnover.PMID 16584805Read ↗

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