Article

Coordination of focal adhesion nanostructure and mechano-signaling drives cardiomyocyte differentiation

2023-11-13

Abstract excerpt

Focal adhesion (FA) organization and signaling are essential for cell growth and differentiation. However, the molecular mechanism that coordinates the FA signaling with cardiomyocyte differentiation has not been fully understood. Here, we provide empirical evidence that BNIP-2, a BCH-domain-containing protein, is the organizer of FA nanostructure that potentiates FA signaling and cell traction force transmission....

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Literature Corpus work: 107e0d1e-40ff-5b27-9df9-bb1e4194e2c0
DOI: 10.1101/2023.11.13.566796

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