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Article

Vinexinß, an atypical "sensor" of retinoic acid receptor gamma signaling: union and sequestration, separation, and phosphorylation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Nov 2010

Lalevée Sébastien, Bour Gaétan, Quinternet Marc, Samarut Eric, Kessler Pascal, Vitorino Marc, Bruck Nathalie, Delsuc Marc-André, Vonesch Jean-Luc, Kieffer Bruno, Rochette-Egly Cécile

Abstract excerpt

The transcriptional activity of nuclear retinoic acid receptors (RARs) relies on the association/dissociation of coregulators at the ligand-binding domain. However, we determined that the N-terminal domain (NTD) also plays a role through its phosphorylation, and we isolated vinexinβ, a cytoskeleton protein with three SH3 domains, as a new partner of the RARγ NTD. Here we deciphered the mechanism of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20634350
DOI: 10.1096/fj.10-160572

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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